ENGLISH

Minicircle and Miniplasmid DNA Vectors: The Future of Nonviral and Viral Gene Transfer

Book information

ISBN
9783527324569, 9783527670420
DOI
10.1002/9783527670420
Language
english
Format
PDF
Filesize
8 MB (8378044 bytes)
Pages
247\247
Orientation
yes
Scanned
yes
Time added
2013-08-01 04:00:00

Description

Content: Chapter 1 Minicircle Patents: A Short IP Overview of Optimizing Nonviral DNA Vectors (pages 1–6): Martin Grund and Dr. Martin SchleefChapter 2 Operator–Repressor Titration: Stable Plasmid Maintenance without Selectable Marker Genes (pages 7–21): Rocky M. CranenburghChapter 3 Selection by RNA–RNA Interaction: Maximally Minimized Antibiotic Resistance?Free Plasmids (pages 23–36): Juergen Mairhofer and Reingard GrabherrChapter 4 Plasmid?Based Medicinal Products – Focus on pFAR: A Miniplasmid Free of Antibiotic Resistance Markers (pages 37–58): Corinne Marie, Mickael Quiviger, Helen Foster, George Dickson and Daniel SchermanChapter 5 Plasmid DNA Concatemers: Influence of Plasmid Structure on Transfection Efficiency (pages 59–69): Christof Maucksch, Bronwen Connor and Carsten RudolphChapter 6 Analytical Tools in Minicircle Production (pages 71–91): Anja Rischmuller, Martina Viefhues, Mareike Dieding, Markus Blaesen, Marco Schmeer, Ruth Baier, Dario Anselmetti and Dr. Martin SchleefChapter 7 Utilizing Minicircle Vectors for the Episomal Modification of Cells (pages 93–113): Orestis Argyros, Suet?Ping Wong, Charles Coutelle and Richard P. HarbottleChapter 8 Replicating Minicircles: Overcoming the Limitations of Transient and Stable Expression Systems (pages 115–163): Kristina Nehlsen, Sandra Broll, Raju Kandimalla, Niels Heinz, Markus Heine, Stefanie Binius, Axel Schambach and Jurgen BodeChapter 9 Magnetofection of Minicircle DNA Vectors (pages 165–176): Flavie Sicard, Cedric Sapet, Nicolas Laurent, Elodie Bertosio, Melanie Bertuzzi and Olivier ZelphatiChapter 10 Minicircle?Based Vectors for Nonviral Gene Therapy: In Vitro Characterization and In Vivo Application (pages 177–188): Dennis Kobelt, Jutta Aumann, Dr. Martin Schleef, Marco Schmeer, Ulrike Stein, Peter M. Schlag and Wolfgang WaltherChapter 11 Episomal Expression of Minicircles and Conventional Plasmids in Mammalian Embryos (pages 189–202): Wiebke Garrels, Khursheed Iqbal and Wilfried A. KuesChapter 12 Tissue?Targeted Gene Electrodelivery of Minicircle DNA (pages 203–213): Sophie Chabot, Muriel Golzio and Justin TeissieChapter 13 Increased Efficiency of Minicircles Versus Plasmids Under Gene Electrotransfer Suboptimal Conditions: An Influence of the Extracellular Matrix (pages 215–225): Vanessa Joubert, Franck M. Andre, Marco Schmeer, Dr. Martin Schleef and Lluis M. Mir

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