ENGLISH

Neuroanatomy and Pathology of Sporadic Alzheimer's Disease

By Heiko Braak , Kelly Del Tredici (auth.)

Book information

Publisher
Springer International Publishing
Year
2015
ISBN
978-3-319-12678-4, 978-3-319-12679-1
DOI
10.1007/978-3-319-12679-1
Language
english
Format
PDF
Filesize
7 MB (7776397 bytes)
Series
Advances in Anatomy, Embryology and Cell Biology 215
Edition
1
Pages
162\168
Time added
2015-02-17 02:00:00
Neurosciences; Pathology; Geriatrics/Gerontology

Description

As indicated by its title, this monograph deals chiefly with morphologically recognizable deviations from the normal anatomical condition of the human CNS. The AD-associated pathology is illustrated from its beginnings (sometimes even in childhood) to its final form, which is reached late in life. The AD process commences much earlier than the clinically recognizable phase of the disorder, and its timeline includes an extended preclinical phase. The further the pendulum swings away from the symptomatic final stages towards the early pathology, the more obvious the lesions become, although from a standpoint of severity they are more unremarkable and thus frequently overlooked during routine neuropathological assessment. For this reason, the authors deal with the hallmark lesions in the early phases of the AD process in considerable detail

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