ENGLISH

Purinergic and Pyrimidinergic Signalling II: Cardiovascular, Respiratory, Immune, Metabolic and Gastrointestinal Tract Function

By R.M. Broad , Joel Linden (auth.) , Professor Maria Pia Abbracchio , Dr. Michael Williams (eds.)

Book information

Publisher
Springer-Verlag Berlin Heidelberg
Year
2001
ISBN
978-3-540-67848-9, 978-3-642-56921-0
DOI
10.1007/978-3-642-56921-0
Language
english
Format
PDF
Filesize
9 MB (9300479 bytes)
Series
Handbook of Experimental Pharmacology 151 / 2
Edition
1
Pages
442\458
Orientation
yes
Scanned
yes
Time added
2013-08-01 04:00:00
Pharmacology/Toxicology; Human Physiology; Immunol

Description

Physiological, pharmacological and molecular biological data generated over the past three decades have demonstrated the existence of two major families of extracellular receptors, the P1, a family of four G-protein coupled receptors and the P2, a family of at least 12 receptors responsive to purine (ATP, ADP) and pyrimidine (UTP) nucleotides through which adenosine and ATP can function as extracellular messengers. The present two-part volume represents an integrated compendium of invited chapters by leading researchers in the area focusing on advances in the understanding of purinergic and pyrimidinergic signaling systems, their role(s) in tissue function and pathophysiology and advances in developing potential new medications based on the modulation of P1 and P2 receptor signaling processes. The volumes will thus provide the reader with a topical, comprehensive and integrated overview of this important area.

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