ENGLISH

Alcohol and Cancer

By Philip J. Brooks PhD (auth.) , Samir Zakhari , Vasilis Vasiliou , Q. Max Guo (eds.)

Book information

Publisher
Springer-Verlag New York
Year
2011
ISBN
978-1-4614-0039-4, 978-1-4614-0040-0
DOI
10.1007/978-1-4614-0040-0
Language
english
Format
PDF
Filesize
6 MB (6216106 bytes)
Edition
1
Pages
243\254
Time added
2013-10-20 05:25:02
Cancer Research; Pharmacology/Toxicology

Description

The World Health Organization has identified chronic alcohol consumption as one of the top ten risk factors for worldwide burden of disease. The International Agency for Research on Cancer has identified alcohol as carcinogenic to humans, including cancers of the upper aerodigestive tract, colon, liver and breast. Alcohol’s actions may be direct e.g. effects on retinoic acid and one-carbon metabolism, or indirect, through metabolites such as acetaldehyde and reactive oxygen species or through various signaling pathways that influence cell cycle and apoptosis that may contribute to carcinogenesis. This volume reviews the state of the art in alcohol-related cancer research in ten chapters.

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