Ciba Foundation Symposium - Taste and Smell in Vertebrates

Description

Volume 1 Methods and Applications of Statistics in Clinical Trials, Volume 1: Concepts, Principles, Trials, and Designs successfully upholds the goals of the Wiley Encyclopedia of Clinical Trials by combining both previously-published and newly developed contributions written by over 100 leading academics, researchers, and practitioners in a comprehensive, approachable format. The result is a succinct reference that unveils modern, cutting-edge approaches to acquiring and understanding data throughout the various stages of clinical trial design and analysis. Volume 2Featuring newly-written material as well as established literature from the Wiley Encyclopedia of Clinical Trials, this book provides a timely and authoritative review of techniques for planning clinical trials as well as the necessary inferential methods for analyzing collected data. This comprehensive volume features established and newly-written literature on the key statistical principles and concepts for designing modern-day clinical trials, such as hazard ratio, flexible designs, confounding, covariates, missing data, and longitudinal data. Examples of ongoing, cutting-edge clinical trials from today's research such as early cancer & heart disease, mother to child human immunodeficiency virus transmission, women's health initiative dietary, and AIDS clinical trials are also explored. Content: Chapter 1 Chairman's Introduction (page 1): O. E. LowensteinChapter 2 The Anatomy and Ultrastructure of Taste Endings (pages 3–30): R. G. Murray and Asia MurrayChapter 3 Physiological and Behavioural Processes of the Sense of Taste (pages 31–50): Carl PfaffmannChapter 4 Physiological Properties of Mammalian Taste Receptors (pages 51–70): Lloyd M. BeidlerChapter 5 Problems of Taste Specificity (pages 71–82): Harald T. AndersenChapter 6 The Influence of the Circulation on Taste Receptors as Shown by the Summated Chorda Tympani Nerve Response in the Rat (pages 83–97): Goran HellekantChapter 7 Neural and Perceptual Responses to Taste Stimuli (pages 99–113): G. Borg, H. Diamant and Y. ZottermanChapter 8 Olfactory Surface and Central Olfactory Connexions in Some Vertebrates (pages 115–149): T. S. Reese and M. W. BrightmanChapter 9 The Olfactory Neuron and the Blood?Brain Barrier (pages 151–176): A. J. Darin De LorenzoChapter 10 Anatomy and Ultkastkuctuke of the Olfactory Bulb in Fish, Amphibia, Reptiles, Birds and Mammals (pages 177–196): K. H. AndresChapter 11 Experiments in Olfaction (pages 197–225): Kjell B. DovingChapter 12 Olfaction in Mammals—Two Aspects: Proliferation of Cells in the Olfactory Epithelium and Sensitivity to Odours (pages 227–250): D. G. Moulton, G. Celebi and R. P. FinkChapter 13 Detection of Hidden Objects by Dogs (pages 251–263): E. H. Ashton and J. T. EayrsChapter 14 Recent Developments in the “Penetration and Puncturing” Theory of Odour (pages 265–291): J. T. DaviesChapter 15 Computer Correlation of Molecular Shape with Odour: A Model for Structure?Activity Relationships (pages 293–312): John E. AmooreChapter 16 Odour Similarity Between Structurally Unrelated Odorants (pages 313–323): M. G. J. Beets and E. T. TheimerChapter 17 Specific Physicochemical Mechanisms of Olfactory Stimulation (pages 325–342): R. H. Wright and R. E. BurgessChapter 18 Electrical Signs of Olfactory Transducer Action (pages 343–356): David OttosonChapter 19 Higher Olfactory Centres (pages 357–378): W. R. AdeyChapter 20 General Discussion (pages 379–387): Chapter 21 Chairman's Closing Remarks (pages 389–391): O. E. Lowenstein