ENGLISH

Cardiovascular Regenerative Medicine: Tissue Engineering and Clinical Applications

By Vahid Serpooshan , Sean M. Wu

Book information

Publisher
Springer International Publishing
Year
2019
ISBN
978-3-030-20046-6;978-3-030-20047-3
Language
english
Format
PDF
Filesize
8 MB (7950686 bytes)
Edition
1st ed.
Pages
XV, 233\242
Time added
2019-09-18 12:19:14
Medicine & Public Health; Cardiology; Regenerative

Description

This book is a comprehensive and up-to-date resource on the use of regenerative medicine for the treatment of cardiovascular disease. It provides a much-needed review of the rapid development and evolution of bio-fabrication techniques to engineer cardiovascular tissues as well as their use in clinical settings. The book incorporates recent advances in the biology, biomaterial design, and manufacturing of bioengineered cardiovascular tissue with their clinical applications to bridge the basic sciences to current and future cardiovascular treatment. The book begins with an examination of state-of-the-art cellular, biomaterial, and macromolecular technologies for the repair and regeneration of diseased heart tissue. It discusses advances in nanotechnology and bioengineering of cardiac microtissues using acoustic assembly. Subsequent chapters explore the clinical applications and translational potential of current technologies such as cardiac patch-based treatments, cell-based regenerative therapies, and injectable hydrogels. The book examines how these methodologies are used to treat a variety of cardiovascular diseases including myocardial infarction, congenital heart disease, and ischemic heart injuries. Finally, the volume concludes with a summary of the most prominent challenges and perspectives on the field of cardiovascular tissue engineering and clinical cardiovascular regenerative medicine. Cardiovascular Regenerative Medicine is an essential resource for physicians, residents, fellows, and medical students in cardiology and cardiovascular regeneration as well as clinical and basic researchers in bioengineering, nanomaterial and technology, and cardiovascular biology. Front Matter ....Pages i-xv Tissue-Engineered Stem Cell Models of Cardiovascular Diseases (Christopher W. Anderson, Jiesi Luo, Lorenzo R. Sewanan, Mehmet H. Kural, Muhammad Riaz, Jinkyu Park et al.)....Pages 1-18 Phenotypic Screening of iPSC-Derived Cardiomyocytes for Cardiotoxicity Testing and Therapeutic Target Discovery (Arne A. N. Bruyneel, Tyler Muser, Vaidya Parthasarathy, Dries Feyen, Mark Mercola)....Pages 19-34 Decellularized Extracellular Matrix-Based Cardiovascular Tissue Engineering (Kristin M. French, Michael E. Davis)....Pages 35-62 3D Bioprinting of Cardiovascular Tissue Constructs: Cardiac Bioinks (Martin L. Tomov, Andrea Theus, Rithvik Sarasani, Huyun Chen, Vahid Serpooshan)....Pages 63-77 Nanobiomaterial Advances in Cardiovascular Tissue Engineering (Michael J. Hill, Morteza Mahmoudi, Parisa P. S. S. Abadi)....Pages 79-106 Bioengineering 3D Cardiac Microtissues Using Bioassembly (Longjun Gu, Jinghan Feng, Donghui Zhang, Pu Chen)....Pages 107-123 From Bench to Clinic: Translation of Cardiovascular Tissue Engineering Products to Clinical Applications (Amanda N. Steele, Y. Joseph Woo)....Pages 125-140 Cardiac Patch-Based Therapies of Ischemic Heart Injuries (Wuqiang Zhu, Danielle Pretorius, Jianyi Zhang)....Pages 141-171 Cell-Based Cardiovascular Regenerative Therapies (Ray P. Prajnamitra, Yuan-Yuan Cheng, Li-Lun Chen, Patrick C. H. Hsieh)....Pages 173-184 Injectable Hydrogels to Treat Myocardial Infarction (Miranda D. Diaz, Karen L. Christman)....Pages 185-206 Regenerative Medicine for the Treatment of Congenital Heart Disease (Elda Dzilic, Stefanie Doppler, Rüdiger Lange, Markus Krane)....Pages 207-221 Cardiovascular Regenerative Medicine: Challenges, Perspectives, and Future Directions (Sean M. Wu, Vahid Serpooshan)....Pages 223-225 Back Matter ....Pages 227-233

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