ENGLISH

Pathology of the Nucleus

By M.D. , J. C. E. Underwood (auth.) , James C. E. Underwood Professor , F.R.C. Path. (eds.)

Book information

Publisher
Springer-Verlag Berlin Heidelberg
Year
1990
ISBN
978-3-642-74670-3, 978-3-642-74668-0
DOI
10.1007/978-3-642-74668-0
Language
english
Format
PDF
Filesize
24 MB (24728613 bytes)
Series
Current Topics in Pathology 82
Edition
1
Pages
343\348
Orientation
yes
Scanned
yes
Time added
2013-08-01 04:00:00
Pathology; Oncology; Cell Biology

Description

New techniques make it possible for investigators to examine and sometimes quantify various aspects of nuclear morphology and function; now they can derive clinically and biologically useful information about the nucleus. This book draws together a series of techniques which have been successfully applied to the study of the nucleus of tumour cells. These are of fundamental importance to researchers in tumour histopathology and medical oncology. Detailed reviews are given of various aspects of the morphology, ploidy and karyotypic status and function of the nuclei in the cells of tumours and preneoplastic lesions. Topics covered include nuclear morphology in tumour diagnosis, the ultrastructure of the nucleus, karyotypic analyses of solid tumours, flow cytometric assessment of nuclear ploidy and other parameters, histomorphometry of the nucleus, and in situ hybridisation.

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