ENGLISH

Biophysical Regulation of Vascular Differentiation and Assembly

By Tiffany M. Sills , Karen K. Hirschi (auth.) , Sharon Gerecht (eds.)

Book information

Publisher
Springer-Verlag New York
Year
2011
ISBN
1441978348, 9781441978349
DOI
10.1007/978-1-4419-7835-6
LCC
QH588.S83 .B54 2011
Open Library ID
OL25033815M
Language
english
Format
PDF
Filesize
7 MB (7535406 bytes)
Series
Biological and Medical Physics, Biomedical Engineering
Edition
1
Pages
254\268
Topic
Biology Biophysics
Time added
2011-06-04 13:46:07
Biophysics and Biological Physics;Biomedical Engin

Description

The ability to grow stem cells in the laboratory and to guide their maturation to functional cells allows us to study the underlying mechanisms that govern vasculature differentiation and assembly in health and disease. Accumulating evidence suggests that early stages of vascular growth are exquisitely tuned by biophysical cues from the microenvironment, yet the scientific understanding of such cellular environments is still in its infancy. Comprehending these processes sufficiently to manipulate them would pave the way to controlling blood vessel growth in therapeutic applications. This book assembles the works and views of experts from various disciplines to provide a unique perspective on how different aspects of its microenvironment regulate the differentiation and assembly of the vasculature. In particular, it describes recent efforts to exploit modern engineering techniques to study and manipulate various biophysical cues. Biophysical Regulation of Vascular Differentiation and Assembly provides an interdisciplinary view of vasculature regulation by various biophysical cues and presents recent advances in measuring and controlling such parameters. This book will be of interest to biologists, biophysicists and engineers who work with vascular differentiation and assembly.

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