ENGLISH

Chemistry and Biology of O-GlcNAcylation

By Wen Yi (editor)

Book information

Publisher
Springer
Year
2024
ISBN
9789819748648, 9789819748631
ASIN
B0D7T27GDY
Language
english
Format
EPUB
Filesize
15 MB (15710627 bytes)
Pages
363\0
Time added
2024-10-20 04:43:26

Description

O-linked N-acetylglucosamine (O-GlcNAc) is a prevalent post-translational modification of numerous intracellular proteins. This modification has recently emerged as a key regulator of various important biological processes, including gene transcription, stress response, metabolic homeostasis, and immune regulation. Given the critical role of O-GlcNAc in normal physiology, increasing evidence has now demonstrated that deregulation of O-GlcNAc is closely associated with the development and progression of various diseases, including neurodegeneration, cardiovascular disease, and cancer. This book provides a comprehensive overview of the current progress and understanding of this modification in biology, and likely provides new research directions in the future.

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