Infectious Diseases in Solid-Organ Transplant Recipients: A practical approach

Description

This book describes a practical approach to the diagnosis, management, and prevention of infectious complications in solid-organ transplant (SOT) candidates and recipients, based on both up-to-date clinical evidence and state of the art expert opinion from world-renowned experts in the field. The book is divided into three parts, the first of which explains risk assessment and the general approach to infectious diseases in the pre-, peri-, and early and late post-transplant periods. The remaining two sections address the prevention and treatment of infection with particular pathogens and the management of specific syndromes, such as pneumonia, CNS infections, UTIs, and skin infections. Infections in SOT recipients – often due to multidrug-resistant organisms – represent a major challenge. Preventive strategies need to be adapted according to the type of allograft and period after transplantation. Moreover, toxicity and drug interaction with immunosuppressive drugs must be taken into consideration when treating infectious complications. In explaining in depth how best to ensure allograft and patient survival, this book will be of value to infectious disease specialists and transplant physicians at all levels of experience. Front Matter ....Pages i-vi Front Matter ....Pages 1-1 The Epidemiology of Infection in Solid Organ Transplant Recipients: A Practical Timeline (Nicolas J. Mueller, Jay A. Fishman)....Pages 3-11 Risk Assessment of Infections in SOT Recipients (Mario Fernández-Ruiz, Nicole M. Theodoropoulos)....Pages 13-24 Pre- and Peri-transplant Period: Screening and Treatment of Infections in the Pretransplant Period, Donor-Derived Infection (Christian Garzoni, Daniel R. Kaul)....Pages 25-38 Prevention of Bacterial, Viral, Fungal, and Parasitic Infections During the Early Post-transplant Period (Camille Nelson Kotton, Christian van Delden)....Pages 39-50 Late Posttransplant Period: Posttransplant Vaccination, Travel Advice, Foodborne Infections (Deepali Kumar, Elisa Cordero)....Pages 51-62 Front Matter ....Pages 63-63 Prevention and Treatment of CMV Infection (and Other Herpes Viruses) (Julian Torre-Cisneros, Atul Humar)....Pages 65-80 Prevention and Treatment of EBV-Related Complications (Sophie Caillard, Michael Green)....Pages 81-91 Prevention and Treatment of Polyomavirus-Associated Diseases (Joanna Schaenman, Chen Sabrina Tan)....Pages 93-105 Prevention and Treatment of Respiratory Virus Infection (Maddalena Peghin, Lara Danziger-Isakov)....Pages 107-129 Prevention and Treatment of Viral Hepatitis (Karen Doucette, Nassim Kamar)....Pages 131-144 Multidrug-Resistant Organisms in Solid Organ Transplantation (Meenakshi M. Rana, Paolo Grossi, Shirish Huprikar)....Pages 145-163 Prevention and Treatment of Mold Infections (Claire Aguilar, Benoit Pilmis, Olivier Lortholary, Shahid Husain)....Pages 165-177 Prevention and Treatment of Yeast and Endemic Fungal Infections (Ahmed Al Hammadi, Luis Ostrosky-Zeichner, John W. Baddley)....Pages 179-199 Prevention and Treatment of Mycobacterial Infections (Yolanda Meije, Eun J. Kwak, José M. Aguado)....Pages 201-217 Prevention and Treatment of Other Opportunistic Infections: Nocardiosis, Toxoplasmosis, Chagas and Pneumocystis Disease (Peter Chin-Hong, Marcelo Radisic)....Pages 219-231 Front Matter ....Pages 233-233 Pneumonia in Solid Organ Transplant Recipients (John-David Aubert, Jordi Carratalà)....Pages 235-243 Management of CNS Infections (Patricia Muñoz, Tina Stosor)....Pages 245-267 Management of Urinary Tract Infection (Carlos Cervera, Francisco López-Medrano)....Pages 269-278 Management of Infections of Devices: Catheter-Related Infections, Pretransplant VAD Infections, Infections of ECMO Devices (Cameron R. Wolfe, Martha L. Mooney)....Pages 279-289 Management and Prevention of Skin Infections (Nicolas Barros, Ricardo M. La Hoz)....Pages 291-304